Different Pieces of the Same Puzzle: A Multifaceted Perspective on the Complex Biological Basis of Parkinson’s disease

The biological basis of the neurodegenerative movement disorder, Parkinson’s disease (PD), is still unclear despite it being ‘discovered’ over 200 years ago in Western Medicine.

Based on current PD knowledge, there are widely varying theories regarding its pathobiology. This article aimed to explore some of these different theories by summarizing the viewpoints of laboratory and clinician scientists in the PD field on the biological basis of the disease. The personal opinions of the thirteen “PD experts” from six continents are presented in this article to achieve this aim. They offer varied views, ranging from toxin exposure as a PD trigger to LRRK2 as a potential root cause to toxic alpha-synuclein being the most critical etiological contributor. Notably, there is also growing recognition that PD might be better defined with multiple subtypes or as multiple diseases, perhaps each with its own unique pathobiology and treatment regimen. Through the utilization of the content of this article, providers will gain knowledge of the most current theories of PD pathogenesis, enabling them to provide more accurate diagnosis and treatment to people with PD. 

 

Syllabus

 

Different Pieces of the Same Puzzle: A Multifaceted Perspective on the Complex Biological Basis of Parkinson’s disease

Journal Article 
Estimated Reading Time: 50-60 Minutes

Quiz

Evaluation

Credit and Certificate Claiming

  

 

Target Audience

This activity is designed to meet the educational needs of:

  • Physicians
  • Physician Assistants
Course summary
Available credit: 
  • 1.00 AAPA Category I CME
  • 1.00 AMA PRA Category 1 Credit
  • 1.00 ANCC
  • 1.00 Participation
Course opens: 
01/08/2024
Course expires: 
01/01/2025
Cost:
$10.00
Rating: 
0

Parkinson’s Foundation adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers, or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Authors:   
  • All authors of this article have no relevant financial relationships to disclosure. For more details, click here.
Activity Director(s)

Svetlana Cvejic

has no relevant financial relationships to disclose at this time.

In support of improving patient care, Parkinson's Foundation is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians 

Parkinson’s Foundation designates this journal activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Physician Assistants 

Parkinson’s Foundation has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent.   

Available Credit

  • 1.00 AAPA Category I CME
  • 1.00 AMA PRA Category 1 Credit
  • 1.00 ANCC
  • 1.00 Participation

Price

Cost:
$10.00
Please login or register to take this course.

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